ʻO ka wehewehe pōkole:
He poepoe, Oval, Oblong, Triangle, Diamond a me kekahi mau ano kūikawā.
| ʻIke Kumu | |
| inoa huahana | Nā Papa Folate |
| Nā inoa ʻē aʻe | Folic Acid Tablet, Ho'ōla Folate Papa, Active Folic Acid Tablet, etc. |
| Papa | Papaʻai |
| Ka nana aku | E like me nā koi a nā mea kūʻai aku He poepoe, Oval, Oblong, Triangle, Diamond a me kekahi mau ano kūikawā. |
| Ola ola | 2-3 mau makahiki, pili i ke kūlana hale kūʻai |
| Hoʻopili | ʻO ka nui, nā ʻōmole, nā blister pack a i ʻole nā koi o nā mea kūʻai aku |
| Kūlana | E mālama i loko o nā pahu paʻa, pale ʻia mai ka mālamalama. |
wehewehe
Hōʻike nui ʻia nā hopena o ka waikawa folic i nā mea ola i kēia mau ʻano: ke komo ʻana i ka metabolism o nā mea genetic a me ka protein; pili i ka hana hānau holoholona; pili i ka huna ʻana o ka pancreas holoholona; hoʻoikaika i ka ulu ʻana o nā holoholona; a me ka hoʻomaikaʻi ʻana i ka pale ʻana o ke kino.
ʻO ka Methyltetrahydrofolate ka mea maʻamau i ka 5-methyltetrahydrofolate, nona ka hana o ka hānai ʻana i ke kino a me ka hoʻonui ʻana i ka waikawa folic. ʻO 5-Methyltetrahydrofolate kahi mea me nā hana ikaika i hoʻololi ʻia mai ka folic acid ma o ke ʻano o nā hopena biochemical i loko o ke kino kanaka. Hiki ke hoʻohana pololei ʻia e ke kino i nā ala metabolic like ʻole e mālama i ka hana maʻamau o ke kino, a laila e pāʻani ana i kahi kuleana i ka hānai ʻana i ke kino.
Hana
ʻO ka waikawa Folic kekahi ʻano o nā huaora B, ʻike ʻia hoʻi he pteroylglutamic acid. ʻO 5-methyltetrahydrofolate ka hana hope loa i ka metabolism a me ka hoʻololi ʻana o ka waikawa folic i ke kino. Ma muli o kāna hana ʻeleu, ua kapa ʻia ʻo ia he ʻeleu. ʻO ka waikawa Folic kahi mea metabolic o ka waikawa folic i ke kino.
No ka mea hiki ke hoʻopili pololei ʻia ka molecular structure o 5-methyltetrahydrofolate e ke kino me ka ʻole o ka hoʻololi ʻana i nā kaʻina hana metabolic paʻakikī, aia ia i loko o nā pūnaewele kino. Hoʻohālikelike ʻia me ka folic acid, ʻoi aku ka maʻalahi o ka hoʻohui ʻana i nā meaʻai no ke kino, ʻoi aku hoʻi no nā wahine pono e hoʻomākaukau no ka hāpai ʻana a me nā wahine hāpai i ka wā hāpai.
ʻO ka waikawa Folic kekahi o nā huaora pono no ka ulu ʻana a me ka hana hou ʻana o nā ʻāpana kino. E pili ana kona hemahema i nā hana physiological maʻamau o ke kino kanaka. Ua hōʻike ʻia nā puke he nui e pili pono ana ka nele o ka folic acid i nā hemahema neural tube, anemia megaloblastic, cleft lip and palate, depression, tumors a me nā maʻi ʻē aʻe.
Nā ʻano ʻino o ka paipu neural (NTD)
ʻO nā pōʻino neural tube (NTDs) he pūʻulu o nā hemahema i hoʻokumu ʻia e ka pani piha ʻole ʻana o ka paipu neural i ka wā o ka ulu ʻana o ka embryonic, me ka anencephaly, encephalocele, spina bifida, etc., a ʻo ia kekahi o nā hemahema neonatal maʻamau. I ka makahiki 1991, ua hōʻoia ka British Medical Research Council no ka manawa mua e hiki i ka folic acid supplementation ma mua a ma hope o ka hāpai ʻana ke pale i ka hiki ʻana mai o nā NTDs a hoʻemi i ka hopena e 50-70%. ʻO ka hopena pale o ka folic acid ma NTDs ua manaʻo ʻia kekahi o nā mea lapaʻau hoihoi loa i ka hopena o ke kenekulia 20.
Anemia megaloblastic (MA)
ʻO ka anemia megaloblastic (MA) kekahi ʻano anemia ma muli o ka hōʻino ʻana o ka DNA synthesis i hoʻokumu ʻia e ka nele o ka folic acid a i ʻole ka huaʻa B12. He mea maʻamau ia i nā kamaliʻi a me nā wahine hāpai. Pono ka hoʻomohala maʻamau o ka pēpē i ka nui o ka waihona folic acid i loko o ke kino o ka makuahine. Inā hoʻopau ʻia ka waihona folic acid i ka wā o ka hānau ʻana a i ʻole ka hānau mua ʻana, hiki mai ka anemia megaloblastic i loko o ka pēpē a me ka makuahine. Ma hope o ka hoʻonui ʻana me ka folic acid, hiki ke hoʻōla koke a hoʻōla ʻia ka maʻi.
ʻO ka ʻakika Folic a me ka lehelehe maʻa a me ka pala
ʻO ka lehelehe a me ka palate (CLP) kekahi o nā maʻi maʻamau o ka hānau hānau ʻana. ʻAʻole maopopo ke kumu o ka lehelehe a me ka pala. Ua hōʻike ʻia ka hoʻohui ʻana i ka waikawa Folic i ka wā o ka hāpai ʻana e pale i ka hānau ʻana o nā keiki me nā lehelehe a me ka pala.
Nā maʻi ʻē aʻe
Hiki i ka nele o ka folic acid ke hoʻopilikia nui i nā makuahine a me nā keiki, e like me ka hāʻule maʻamau, hānau mua ʻana, haʻahaʻa haʻahaʻa haʻahaʻa, ʻaʻai ʻai ʻana o ka pēpē a me ka ulu ʻana. He nui nā palapala e hōʻike ana e pili ana ka maʻi o Alzheimer, ke kaumaha, a me nā maʻi maʻi neurological i nā keiki hānau hou a me nā ʻeha lolo ʻē aʻe e pili ana i ka nele o ka folic acid. Eia kekahi, ʻo ka nele o ka folic acid hiki ke hoʻoulu i nā maʻi koko (ka maʻi ʻōpū, ka maʻi bronchial, ka maʻi esophageal, colorectal cancer, etc.) ulu maikaʻi ʻole. Hiki i nā mākua ke nele i ka waikawa folic a inu i ka waiʻona nui ke hoʻololi i ke ʻano o ka mucosa ʻōpū.
Nā noi
1. ʻO nā wahine i ka wā o ka hoʻomākaukau ʻana i ka hāpai ʻana a me ka hāpai mua ʻana.
2. Nā kānaka me ka anemia.
3. Nā kānaka me ka homocysteine kiʻekiʻe.
