ʻO ka wehewehe pōkole:
Helu CAS: 1197-18-8
ʻAno molekole: C8H15NO2
kaumaha molekalale: 157.21
Hoʻolālā kemika:
| ʻIke Kumu | |
| inoa huahana | ʻAka Tranexamic |
| Papa | Papa Hoʻomaʻamaʻa |
| Ka nana aku | Keʻokeʻo a ʻaneʻane keʻokeʻo, pauka crystalline |
| Hoʻāʻo | 99% |
| Ola ola | 2 makahiki |
| Hoʻopili | 25kg / pahu |
| Na Waiwai Kemika | Hiki ke hoʻoheheʻe ʻia i loko o ka wai a me ka waikawa acetic glacial a hiki ke hoʻoheheʻe ʻia i ka ethanol a hiki ʻole ke hoʻoheheʻe ʻia i ka etera. |
wehewehe
ʻO ka waika Tranexamic kahi derivative o ka aminomethylbenzoic acid, a he ʻano lāʻau antifibrinolytic e hoʻōki i ke koko. ʻO ka hana hemostasis o ka waikawa tranexamic e like me ka aminocaproic acid a me ka aminomethylbenzoic acid, akā ʻoi aku ka ikaika o ka hopena. ʻO ka ikaika he 7 a 10 mau manawa o ka aminocaproic acid, 2 mau manawa o ka aminomethylbenzoic acid, akā ua like ka toxicity.
ʻO ka hana kemika o ka waika tranexamic e like me ka lysine, ka hoʻokūkū hoʻokūkū o ka plasmin kumu i ka fibrin adsorption, e pale i kā lākou hoʻoulu ʻana, pale i ka protein fiber ʻaʻole e hoʻohaʻahaʻa ʻia e ka plasmin a hoʻoheheʻe ʻia, a hiki i ka hemostasis. Hoʻohana ʻia i ka mālama ʻana i ka hyperthyroidism fibrinolytic fibrinolytic kumu nui, e like me ka obstetric hemorrhage, renal hemorrhage, hemorrhage o ka hypertrophy o ka prostate, hemophilia, pulmonary tuberculosis hemoptysis, ʻōpū koko, ma hope o ka hana ʻana o ke ake, akemāmā. , spleen a me nā viscera hemorrhage ʻē aʻe; Hiki ke hoʻohana ʻia i ka ʻoki ʻana i ka wā o ke kahe koko ʻole, etc.
He hopena koʻikoʻi ka waika tranexamic maʻi i nā maʻi nahu nahu, dermatitis a me ka eczema, purpura maʻalahi, urticaria maʻi, urticaria sex artificial, hū a me ka pele. A he hopena kekahi i ka erythroderma, scleroderma, systemic lupus erythematosus (SLE), Erythema multiforme, shingles a me alopecia areata. Maikaʻi nō hoʻi ka mālama ʻana i ka hopena angioedema hoʻoilina. I ka mālama ʻana iā Chloasma, ʻoi aku ka maikaʻi o ka lāʻau lapaʻau ma kahi o 3 mau pule, ʻoi aku ka maikaʻi o 5 mau pule, he 60 mau lā. Hāʻawi ʻia i ka waha ma nā ʻano o 0.25 ~ 0.5 g, i ka lā 3 ~ 4 mau manawa. Hiki i kekahi mau maʻi ke nausea, luhi, ʻehaʻeha, ʻehaʻeha o ka ʻōpū, a me nā hopena ʻaoʻao ma hope o ka hemo ʻana o nā hōʻailona.
Nā hōʻailona
ʻO nā kahe koko like ʻole i hoʻokumu ʻia e ka hyperfibrinolysis mua a i ʻole ka maʻi maʻi; ʻO ke kūlana hyperfibrinolytic lua ma muli o ka hoʻolaha ʻana o ka coagulation intravascular. Mai hoʻohana maʻamau i kēia huahana ma mua o ka heparinization.
ʻO ka ʻeha a i ʻole ke kahe koko ʻana i loko o ka ʻiʻo a me nā ʻāpana me nā mea hoʻoulu plasminogen nui e like me prostate, urethra, lung, lolo, kōpū, adrenal glands, a me thyroid.
He mea kū'ē i ka tissue plasminogen activator (t-PA), streptokinase, a me urokinase.
ʻO ka hemorrhage fibrinolytic i hoʻokumu ʻia e ka hoʻohemo ʻana, ka wehe mua ʻana o ka placental, ka hānau ʻana a me ka embolism wai amniotic; a me ka hoʻonui ʻana i ka menorrhagia ma muli o ka pathological intrauterine fibrinolysis.
ʻO ka cerebral neuropathy maʻalahi ke koko, e like me ka subarachnoid hemorrhage a me ka intracranial aneurysm hemorrhage, ʻoi aku ka maikaʻi o ka hopena o Amstat i kēia ʻano ma mua o nā mea anti-fibrinolytic ʻē aʻe. Pono e uku nui ʻia i ka hopena o ka edema cerebral a i ʻole ka cerebral infarction.
No ka mālama ʻana i ka edema angioneurotic hereditary, hiki ke hōʻemi i ka helu a me ka paʻakikī o nā episodes.
Hoʻohana ʻia i nā maʻi me ka hemophilia no kā lākou hemorrhage ikaika i hui pū me nā lāʻau ʻē aʻe.
ʻO ka poʻe maʻi hemophilia me ka helu VIII a i ʻole ka helu IX hemahema i ko lākou ʻoki ʻana i nā niho a i ʻole ke ʻoki waha i ka hihia o ke kahe koko.
